The Foundation

We are the largest nonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees should reflect the rich diversity of the global populations we aim to serve. We provide an exceptional benefits package to employees and their families which include comprehensive medical, dental, and vision coverage with no premiums, generous paid time off, paid family leave, foundation-paid retirement contribution, regional holidays, and opportunities to engage in several employee communities. As a workplace, we’re committed to creating an environment for you to thrive both personally and professionally.

The Team

Global Health

The Gates Foundation Global Health division harnesses advances in science and technology to save lives in poor countries. We focus on the health problems that have a major impact in developing countries but get too little attention and funding. Where shown tools exist, we support sustainable ways to improve their delivery. Where they don’t, we invest in research and development of new interventions, such as vaccines, drugs, biologics, and diagnostics. Our work in infectious diseases focuses on strategies to fight and prevent HIV/AIDS, malaria, tuberculosis, neglected tropical diseases, enteric and diarrheal diseases and pneumonia. These strategies are supported by functional teams that focus on Discovery & Translational Sciences, Vaccine Development & Surveillance, Integrated Development (IDev), and Innovation Introduction.

Integrated Development

The Integrated Development (IDev) team is a cross-functional team that supports Foundation Program Strategy Teams (PSTs) by providing technical expertise in the following areas: Quantitative Sciences (QuantSci), Regulatory Affairs (RA), Design, Analyze, Communicate (DAC), Chemistry, Manufacturing and Controls (CMC). IDev plays a critical role in advancing the foundations portfolio of products and building up the broader global health ecosystem.

Your Role

The Gates Foundation seeks a Senior Program Officer (SPO) in Pharmacometrics to join the Quantitative Sciences (QuantSci) team within the Integrated Development (IDev) Group. You will lead global initiatives to develop and apply advanced pharmacometric methods—including AI-driven modeling and simulation—to optimize drug development for diverse populations, particularly in low- and middle-income countries (LMICs). By advancing Model Informed Drug Development (MIDD), you will enhance drug efficacy, streamline clinical trials, and accelerate access to new therapies. Your role will be instrumental in ensuring that these innovative treatments reach those who need them most, addressing unique health challenges with efficiency and impact. Collaborating with leading experts, you’ll drive solutions that make a tangible difference in global health.

What You’ll Do

• Strategic Leadership: Define the strategic vision for pharmacometrics, aligning with global health objectives, and lead initiatives integrating pharmacometric approaches into MIDD programs for LMICs.
• Subject Matter Expert (SME) Management: Foster and oversee a diverse network of SMEs, coordinating their contributions to Foundation-led projects and managing associated contracts to drive the success of these initiatives.
• Grant Making and Management: Oversee a portfolio of grants by identifying funding opportunities, crafting proposals, establishing success metrics, and ensuring initiatives deliver measurable and sustainable health improvements.
• Driver of Innovation: Lead the adoption of emerging trends and technologies in pharmacometrics—including AI/ML applications—and promote open-source tools to accelerate drug development and research, particularly in LMICs.
• Partnership Building: Forge and maintain robust relationships with global health partners, including international health agencies, non-profits, academic institutions, and private sector entities.
• Consultation and Support: Provide critical consultation and thought partnership to Foundation partners and external collaborators to advance drug development initiatives, ensuring successful implementation of grants and technical innovations.
• Communication and Advocacy: Represent the Foundation at scientific and policy forums, advocating for the integration of pharmacometrics in global health strategies and engaging stakeholders to communicate its value.

Your Experience

• Advanced degree (Master’s, PhD, PharmD, MD) in pharmacometrics, pharmaceutical sciences, engineering, or a related field.
• Minimum of 10 years in the pharmaceutical industry or related field, focusing on the application of pharmacometrics and/or systems pharmacology to drug development.
• Technical MIDD and Quantitative Background: Significant experience applying pharmacometric analyses to inform decision-making in drug development, particularly in LMICs.
• Regulatory Expertise in Pharmacometrics: Proven experience collaborating with regulatory bodies on pharmacometric analyses in submissions, using modeling to support regulatory decisions.
• Leadership Excellence: Extensive leadership experience in quantitative analysis supporting medical product development, with a proven ability to build and inspire collaborative relationships.
• Communication and Advocacy: Exceptional ability to convey complex technical information to diverse audiences, build consensus, and drive strategic decisions with senior stakeholders across sectors.

Other Attributes

• Open-Source and AI Experience: Experience contributing to open-source projects and familiarity with AI/ML technologies is highly desirable.

*Must be able to legally work in the country where this position is located without visa sponsorship.

The salary range for this role is $229,100 to $355,200 USD. We recognize high-wage market differences in Seattle and Washington D.C., where our offices are located. The range for this role in these locations is $249,600 to $386,900 USD. As a mission-driven organization, we strive to balance competitive pay with our mission. New hires salaries are typically between the range minimum and the salary range midpoint. Actual placement in the range will depend on a candidate’s job-related skills, experience, and expertise, as evaluated during the interview process.

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Hiring Requirements

As part of our standard hiring process for new employees, employment will be contingent upon successful completion of a background check.

Candidate Accommodations

If you require assistance due to a disability in the application or recruitment process, please submit a request here.

Inclusion Statement

We are dedicated to the belief that all lives have equal value. We strive for a global and cultural workplace that supports ever greater diversity, equity, and inclusion — of voices, ideas, and approaches — and we support this diversity through all our employment practices.

All applicants and employees who are drawn to serve our mission will enjoy equality of opportunity and fair treatment without regard to race, color, age, religion, pregnancy, sex, sexual orientation, disability, gender identity, gender expression, national origin, genetic information, veteran status, marital status, and prior protected activity.